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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2779ec3199b5a374b1c3825b7a4a0a2538b6e312562f76c7e205e48612d32e3' 
  AND token = 'CQui98fc43jeY5aA73RL/swG4ASHAfvwt5sZx/3GmL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}