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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1543d07d83191c76a657371d92184d68eade4a4cffa103fb302a9cca41da7349' 
  AND token = '4o7KCTp9FTH/Hwc/TB2nM/glXSdM4uxyk3PX0QLSZoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}