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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e0559d5d18bf616e297822bd644ab61a934fed3d81fb3fc1d3598a605298e4' 
  AND token = 'Jqr9RW3vMKrW9oHW5cuMshd1LbB22h4oJ5j7kdF3JmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}