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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7887047f69594ef83968465c2efd6901799a97b370820b66e863603016ac45' 
  AND token = '1TrRoUh6zjfbmCZltzFgnHMsx1qPvtYuImne9PUqXNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}