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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f7b7b540e81f36eeb8a34a82154d3b64b288a59731078108dc4dc36c3b5957' 
  AND token = 'z5M1b+JRSRcqyMuR8dZyzw30P0QsnUYIBkjIx6GQqnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}