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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78dd21ce30fa46f3a6cd49b35c45153cb265f2398f7e033f0f8b01e57355dc99' 
  AND token = '0fHMMILpojhrfkJ2p6qKE6Ghk2+VX2H2DF2SgWCADUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}