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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bb434ba416efa20b90803f53bce5c46d17ef7fd5dbc2c2a3c3e4898df304349' 
  AND token = '+wDROLe2VYtC/Uzuc+azyzyEVis7bPsO2tzFD3DfCv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}