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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b04587849849b1047068add613266491e3cd2737e28efe5881442257c2bc7ec3' 
  AND token = 'VFdpPbM4ZeidODIbs8DJ3QpXa1aM9/aPw0yHacnOOjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}