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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07978e2309a4a49d084b9eea77b335f841af56ec4ac64c5244e5b9caee9db408' 
  AND token = 'Z8xivr7esvR+UzZoG4ZufwmkvQj9oCD0iHNT8CbzD6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}