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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6721bf0277e1c9e46e6abcae0468c9955515ff1a1041f98d2f1968bc9e863d57' 
  AND token = 'cRT3ox0/quDxBB7fjcGJt2YSxtIGjQkgP3AxmpGSv48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}