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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2782afae8db82b7fec7afb0110ef0437385b227b5af55357f760a6d0e7031fe9' 
  AND token = 'Glmgso5kyupqi239ygwHXg2bMZNzOdahNJwQPIs2yRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}