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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701a344ca683d46579f2271077e99e4b4292c2ebe2021ee20b2d5a83b5c17441' 
  AND token = '5OCvfQHIt7LVyStX/9VYzg2hbKZchdtS1/NwMzmlArE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}