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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0b2aeff9717378593abb7203cf3fb1b5b4ef38dc3136ad04d277ef5943642d' 
  AND token = '99wIKp1DuFqXmSUkBFNRYcq6o0XFiDOFlXNt8I649pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}