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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e206a66e447d5c0fdf99f4f1cf9bb748c6df7d55b21bf8eb3a59a6313387f2d' 
  AND token = 'xtOA8tYLB5y9oLqx4cKgjingndWP1+SigeWA+IEDCKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}