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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859a4703d6049f3feb8356b508727d0324a6be7df4bcd18c7c81cb9a22b7eb58' 
  AND token = 'avjTtsteDwPIthV+YI9Taf0mSiZyFgjCMIX97Dlo1dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}