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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79168971605efe92b9f193471823fb544d3f72ab7267b04280c2972a1aa5a6b9' 
  AND token = 'PeGZIDQBPY2sb5eXFMd65IgyuY1Gkeg99I35F5ymJ9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}