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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335cf3ffc674527d561deeac88ad81a0e737d0d4288eecd1b95d19aa269808d1' 
  AND token = 'c6RM/QPpZhgYqtDV/sI939ebE6zYoqmQgq54PVtq4KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}