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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4c16a20726070107bb5d97b1fe5f15b7aa019ac73297804e09c14d7f2b307d' 
  AND token = 'sJGjwlGD6G0zUtJuBcRLzaBFGR4yG/eRvVQ53RfnX0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}