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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ed66b88093e19d39cbf3ec1bd97c380d0d00d27d1756699646e2cb3484d090' 
  AND token = 'jl7lZCWXqmZzi2zmkUqI4IZOJRGNWUaiUwD9anTfMt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}