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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e44143b6014a861cd79bb57839a39c38acf16f34b52e86a0aa5676e6a94968' 
  AND token = 'VRvRxA1zkS80QP60bp7ml/pAOWrNYHC42CTUafQ09Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}