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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a74fab8b1add8d0d8037092dea835aa0c4d039a832eadf09da8552c7eb5c8e' 
  AND token = 'Zxl0ou8x/ByJDp51Uww/eMNpjIrE1bwsGi4h6+cbDaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}