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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5ccc9163f4d51fcf89dd783351895a5740b56e064dce8a87ab69a313be4ef0' 
  AND token = 'jwRNb5FerkvnUbHEXGkWrgXadYKY5Oj1ufZROx6Kzmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}