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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b22642c2161a2ec023076114c0bca35d25df9d28c50b41ffad32dd9dff846e' 
  AND token = 'EyjneOc8d5/yEJzPzzoUnr/DeJLPE1J0D0PB8yUc9Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}