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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47abb3777e234a03ce099218bf90e7a7cc674edacf82fa702c7b9bf810d05490' 
  AND token = 'wO4KWetEn32NcVn4Sp/2KlKfqaM12DfCwRFw0wYkGR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}