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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0ecb01fb3d7fde44b3b33ec4abf4515e45a377e27b9f3ed948e04675ed61e4' 
  AND token = 'sjW3lAo1THrexrykvIK+F/z2jybmYMrxtByIbwlDMC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}