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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22dff8522c4093e6d65f467956681cd2a1ac0e400a3eace878dc5f2ef5bdfd7' 
  AND token = 'Wkko75MNDq26BILZASIfh132KBY56owRUCY8e1/LKb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}