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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb647625e4010aa8d78dc5a6fc21a69b809a0a3413d84960786b19af1ed798b1' 
  AND token = 'zdIaUF85yldmgbbOVT35khC5HC8p7zXizgAWbvZgiSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}