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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7702220e0200b9e2c6b19d51a90133b494c49eedfc22f97e77a4d3a376b404' 
  AND token = '9p1d6fVbKN+VFw+Cn0uuZU3cxLZ41tHJPIzu2eXBxzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}