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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35384beb03b87eb2b277302572ddb2529e750b56e66b71ebe840b674f0cc6d8e' 
  AND token = 'W8zDaZymj/9ZgxaAhZ+mZyZPgvh6XycgP6pWlDSutxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}