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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '854f9a4d25a146b3d456f9120a4d4c3e1046dbfd79813b60cde216f1c52725bf' 
  AND token = '3McQQpYraP+UMXI/cuFMd1igx3QaqKC2Vxyj0uL/Z3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}