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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7f1029c852046357f14d58e52c7b1f20a456e3ac43c3fe784e29b311dd7d629' 
  AND token = '2kdx5/bKAGkryZjXbRoAKLAQW5yCqyv16lQoHbw3nn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}