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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b026594d11c1bdb11b30f16506db187c19251dedefdf818c0c76cf3ad566fea' 
  AND token = 'RGJ16EAGE2AEJtQ3cTqJ+SVO2ZEJPqLE5czDRolCFRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}