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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dac8812a46b92e6c440618a0e8b93ec9ae9e2df624a69be48a3e86774f41b538' 
  AND token = 'F9ARqUMy6Ccw/3SSsKf6DOPwxrLAY7gKj3100EZ2GyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}