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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c91eca97c5692f54ba4e2175b57d3167cfd3890830c69b4275dd5d0d1f1de5' 
  AND token = 'OCu4lKISEX+UH1FmT+/jGfPGa26Vx3iHA4tYT1Px7jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}