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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1b17b01c3efe8fffeea8f58c7a5db03d8a4c4c3293346197b5e8e03b1195f5' 
  AND token = '9rP2FTM0PoxBgDJNCPNiR18jTKgRm7pWdS9JA2cYbIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}