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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d8124479e50a5ac6ade78457bfff322f0bb25e325f60b9b2404180a07dfe60' 
  AND token = '33oz6dF/w/xLmyH8i3aM9k8aada+SPqnkevUZyQYeYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}