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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c6a617c6ba5edd35e2c2064f4cfee67b9b1a6f65d7dd721bea1307814420e0' 
  AND token = 'Lc8j92aRUcZYN/v3bajo0MtHoP7jrWzV8oliGp5RF3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}