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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb6753233f806402ed1a1c1c0b8f067d023870ce5aaef373824284bb67e0da6' 
  AND token = 'Ry7Axtc07fo2SgoEndxMvWuQSFQ7gfoaq1w/jal1++Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}