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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c35c89c65f8276a9cb4dd1d711f931872c542050daf560e7a33354daa5af2f1' 
  AND token = '7eG8xNkvD14qnZ94XSmH2SvIEgMFRiyHkwj0008s42s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}