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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a4a6e7f1720fd245a86f4e94e103eec7c683c891b602411d376599bb7a81c8' 
  AND token = '9b/br1LmIWmEaMIkotzmQHhHNRU424rU7Dp2i7i+vWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}