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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480a5a0a0399687c0d766d8edc4f6010a740553575d4547cf536b7de7bf4e352' 
  AND token = '2qpVx85d7HBJaEiWyHlgX/A5l0cXWrtVrurXxwZKRto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}