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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72ba7cd4af38a55f986fc0313917d80fbfeddcd456ceaf7b7f436de5da6b3d8' 
  AND token = '5rgzKXvfn2nZmPcV3qpnn5fYlRpJhWyUb0uX75Vpsis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}