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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5762deb5e016bb57342cd888e7c54b7ed3b2d248b73452c98d25f29f19b9da4e' 
  AND token = 'PpnIMQLFcsOuxXgMuGMjjmPEobyJRW7zgkeiol9GoH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}