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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41310fc3f28161ca12bbe3d5faf52e7e0ff48b52cd4461062071286fb9207a72' 
  AND token = '4Ge4q1iLEXm2ZAAAyUuahntF2gPr3G2Tk9/+VF+rVwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}