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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c09935f28160d8782a7fc32cc5dc4e86f37327b03fc8b1c64ba649a6c73e4b16' 
  AND token = 'qlkW4lpP4bSY6mWoIdbK58A8VmBh4DGni76wCWJSFaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}