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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4c9d149ddb57664998146ab3fd09c1d3dffd46cb963cdc5a1f2af8afc45f6d' 
  AND token = '2VxCiDG/IMi4GB4k8jnJHkc+jHa3e/LH9FBPJlDbdbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}