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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a501efb3ba04d4291a2b91b540044c2bf0b998b3ca8ad055a5485c1c5c43c25e' 
  AND token = '5IZmAvNM7KypqC4dW4L2fJCh5OCH6o8YJRdCZG2/KoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}