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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ff21b18b4121082b908c353b549baeaaaa99abb9ea98a1f6550090cce60a3fb' 
  AND token = 'KEZmyxzYRsjk+roVx3mrXieXFN1WMRj6oxF5NWI98lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}