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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08325c1f146d906c93132ca809c403a6d129dff73d806a51c08e9689c0022a6' 
  AND token = '6vMKaJIcE12I7MWVAr18KXBUofRmhYN2sTUhB+X8Eao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}