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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2876d2470fc53c459543e6ccdb9d4b706c869de2e988f5b595285868d3c7ba38' 
  AND token = 'ZDd+EyZ3VAeOCZsBfV7GIE1p0LYxH/KnfsJWOfoEbTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}